Ovarian Insufficiency is the loss of function of the ovaries. Women are usually affected after menopause, but ovarian failure may also occur in young women. Ovarian Rejuvenation aims to restore ovarian function and enable natural fertilization.
If complete ovulation of the egg (ovum) does not occur in the ovaries, fertilization by the sperm is impossible. In young women this condition is called Ovarian Failure or Premature Ovarian Insufficiency (POI). Another important task of the ovaries is the production of female sex hormones that control the menstrual cycle. Often, menstruation is irregular or completely absent (amenorrhea). Depression and low bone density can be caused by the lack of estrogen.
One differentiates between primary ovarian failure, in which the problem originates from the ovaries themselves, and secondary ovarian insufficiency. In the latter, the cause lies in central brain areas, for example in the region of the pituitary gland, which is responsible for the stimulation of the ovaries.
For the diagnosis of ovarian failure, a comprehensive hormone analysis is helpful in distinguishing the two types of ovarian failure. The ovaries are usually examined by ultrasound.
Treatment of ovarian insufficiency with bioidentical hormones (Bioidentical Hormonal Replacement Therapy, BHRT)
The therapy of ovarian failure depends on its cause and the main symptoms. For example, the intake of calcium and vitamin D may be useful for strengthening the bones.
If the hormone analysis reveals that the body lacks female sex hormones, they can be given as part of a therapy. Further hormonal imbalances can have a negative impact on the function of the ovaries and can be treated by targeted therapy with bioidentical hormones (BHRT). Thereby the function of the ovaries can be stimulated.
Secondary ovarian failure can originate from different organs. Equally varying is their treatment.
Ovarian Rejuvenation with PRP and Stem Cells
In cases where factors such as impermeability of the fallopian tubes have been excluded and ovulation does not occur despite hormonal balance, the ovaries can be regenerated and stimulated to function by treatment with growth factors, Platelet-Rich Plasma (PRP), or Mesenchymal Stem cells (MSC) and Stromal Vascular Fraction (SVF) from the patient’s body fat.
The therapy for ovarian rejuvenation is performed on an outpatient basis. First, some fat from the patient’s body is harvested from which the stem cells are extracted. Immediately afterwards, stem cells and PRP are injected in the area of the ovaries through the vagina. If, as a result of the treatment, the function of the ovaries re-establishes, procreation is possible in a natural way.